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Common Drug Interaction Warnings

These are general awareness guidelines. Always consult your nephrologist before starting or stopping any medication.

NSAIDs (Ibuprofen, Diclofenac) + ACE Inhibitors/ARBs

NSAIDs reduce the kidney-protective effects of ACE inhibitors/ARBs and can cause acute kidney injury. Avoid NSAIDs if you have CKD.

Potassium Supplements + ACE Inhibitors/ARBs

This combination can cause dangerously high potassium levels (hyperkalemia). Monitor potassium levels regularly.

Metformin + Severe CKD (Stage 4-5)

Metformin should be dose-adjusted or stopped when GFR drops below 30 due to risk of lactic acidosis. Discuss alternatives with your doctor.

Tacrolimus + Grapefruit / Erythromycin

Grapefruit and certain antibiotics increase tacrolimus levels, risking toxicity. Transplant patients must avoid grapefruit entirely.

Calcium Supplements + Iron Supplements

Calcium interferes with iron absorption. Take these at least 2 hours apart for proper absorption.

Common Kidney Medications

Reference guide for medications frequently prescribed in nephrology

Telmisartan / Losartan

ARB — Protects kidneys by reducing proteinuria and controlling blood pressure. First-line for CKD with diabetes or hypertension.

BP / Kidney Protection

Dapagliflozin (Forxiga)

SGLT2 Inhibitor — Slows CKD progression, reduces proteinuria, and protects the heart. Breakthrough medication for kidney disease.

CKD Protection

Torsemide / Furosemide

Loop Diuretic — Removes excess fluid in CKD patients with edema. Monitor electrolytes regularly.

Fluid Management

Erythropoietin (EPO)

Hormone injection — Treats anemia of CKD by stimulating red blood cell production. Given subcutaneously 1-3 times/week.

Anemia

Iron Sucrose (IV Infusion)

Intravenous iron — For iron deficiency anemia in CKD/dialysis patients. More effective than oral iron in advanced CKD.

Anemia

Calcium Acetate / Sevelamer

Phosphate Binder — Controls high phosphorus levels in CKD Stage 4-5 and dialysis. Take with meals.

Bone Health

Calcitriol (Active Vitamin D)

Controls secondary hyperparathyroidism and calcium metabolism in CKD. Different from regular Vitamin D supplements.

Bone Health

Tacrolimus / Cyclosporine

Immunosuppressant — Prevents organ rejection after kidney transplant. Requires careful blood level monitoring.

Transplant

Sodium Bicarbonate

Corrects metabolic acidosis in CKD. Maintaining normal bicarbonate levels may slow CKD progression.

Electrolyte Balance

Medical Disclaimer: This tracker is for personal organization only. It does not constitute medical advice. Never start, stop, or change medications without consulting your nephrologist. Drug interaction information is general guidance — always verify with your doctor or pharmacist.